Researchers currently funded

Researcher	Institution	Title
Dr. Lan Zhou	CASE WESTERN RESERVE UNIVERSITY	The Role of Aberrant Notch Signaling in the Chronic Myeloproliferative Disorder Induced by Fucosylation Deficiency
Dr. Zhilin Hu*	CASE WESTERN RESERVE UNIVERSITY	Bronchoscopic OCT imaging to identify premalignant changes in the pulmonary epithelium
Dr. Yanwu Yang	CASE WESTERN RESERVE UNIVERSITY	Structural Mechanism of How SnoN-FHL2 Complex Activates Wnt/beta-catenin Signaling
Dr. Patrick Ma*	CASE WESTERN RESERVE UNIVERSITY	High-Throughput Cell-Based MET Inhibitor Development For Lung Cancer Individualized Therapy
Dr. James Mulloy*	CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER	Genetic screen for pathways cooperating with AMLl -ETO in leukemia induction
Dr. Vrushank Dave	CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER	PTEN/PI3K/AKT Pathway in Lung Cancer
Dr. Samir Acharya	THE OHIO STATE UNIVERSITY	Role of Mismatch Repair in Cell Survival
Dr. Robert Baiocchi	THE OHIO STATE UNIVERSITY	Role of the Arginine Methyltansferase PRMT5 in B cell Transformation
Dr. Harold A. Fisk	THE OHIO STATE UNIVERSITY	Regulation of the Centrosomal Degradation of the Mps1 Protein Kinase
Dr. Rami Aqeilan	THE OHIO STATE UNIVERSITY	Role of the WW Domain-Containing Oxidoreductase (WWOX) Gene in Skeletal Development and Bone Neoplasia
Dr. Ana Luisa Kadekaro*	UNIVERSITY OF CINCINNATI	Defining the Regulation of p53 and its Pathway by Autocrine/Paracrine Factors in UVR-irradiated Human Melanocytes
Dr. Rodney DeKoter	UNIVERSITY OF CINCINNATI	A Mouse Model of Myeloid Leukemia Caused By a Novel Hypomorphic Mutation of PU.1
Dr. Shan Lu*	UNIVERSITY OF CINCINNATI	The molecular pathway of Vav3-mediated androgen receptor activation in prostate cancer
Dr. Steve M. Patrick	UNIVERSITY OF TOLEDO	RPA Phosphorylation and DNA Binding: Roles in the Nbs1/MRN Interaction and ATR Signaling
Dr. Steven J. Sucheck	UNIVERSITY OF TOLEDO	Solid Phase Synthesis of Cancer Antigenes Containing Decarboxylative Ligation Functionality
Dr. Fan Dong	UNIVERSITY OF TOLEDO	Gfi-1 in the Regulation of p21 Cip
* indicates 2nd year of 2 year project

Researchers funded for the
2005-2007 funding cycle

Dr. Xue-Feng Bai	The Ohio State University	Novel Strategies to Overcome Antigenic Drift
Dr. Susan Cole	The Ohio State University	Modulation of Lunatic fringe gene activity and Notch signaling in the segmentation clock
Dr. Stefan Niewiesk	The Ohio State University	Induction of oncolysis in Adut T Cell Leukemia Through Heat Shock Protein Induction and Measles Virus Co-Infection
Dr. Marie-Odile Parat	The Cleveland Clinic Foundation	Role of Caveolin-1 in H-Ras Targeting
Dr. Douglas L. Pittman	Medical University Of Ohio	Characterizing the RAD51D E233G High-Risk Breast Cancer Allele
Dr. Duxin Sun	The Ohio State University	Targeted Prodrug Delivery for Cancer Therapy
Dr. Craig R. Tomlinson	University Of Cincinnati	Global gene expression profiles for the very early prediction of breast cancer
Dr. Laura A. Kresty	The Ohio State University	Reversing Epigenetic Changes Through HDAC Inhibition: A Tool for Cancer Prevention

Researchers funded for the
2003-2005 funding cycle

Dr. Werner Tjarks	The Ohio State University	Synthesis of Boron and Gadolinium Containing Texaphyrins For NCT of Head and Neck Cancer
Dr. Yolanda Sanchez	University Of Cincinnati	The Role of Sfp1 in the Response to DNA Damage
Dr. Susanne Wells	Children's Hospital Research Foundation	DEK Oncogene Regulation by the Human Papillomavirus E6 Proteins

Researchers funded for the
2002-2004 funding cycle

Dr. Marina Antoch	The Cleveland Clinic Foundation	Diagnostic Markers Of Mammalian Circadian Clock Function
Dr. Denis C Guttridge	The Ohio State University	NF-kappa B Regulation of Cell Growth Control in G1/S
Dr. Subrata Haldar	Metrohealth Medical Center	Epigenetic Inactivation of Apaf-1 in Metastatic Melanoma
Dr. Hung-Ying Kao	Case Western Reserve University	The Role Of GPS2 In Transcriptional Co-Repressor SMRT-Mediated Repression Activity
Dr. Hua Lou	Case Western Reserve University	Medullary Thyroid Carcinoma As A Model To Study Alternative RNA Splicing
Dr. Narendra Narayana	Case Western Reserve University	Crystal Structure Determination of DSX-DNA Complex
Dr. Nywana Sizemore	The Cleveland Clinic Foundation	Molecular Targets Of The PI3K/AKT/IKK Pathway In Breast Cancer
Dr. Karl Andrew Werbovetz	The Ohio State University	Characterization of the Tubulin Peptide Binding Site
Dr. Ying Xia	University Of Cincinnati	Role of MEKK1 in Anticancer Treatment
Dr. Kam Chi Yeung	Medical College Of Ohio	Substrates of Raf-1 Protein Kinase

Researchers funded for the
2001-2003 funding cycle

Dr. Zalfa Abdel-Malek	University Of Cincinnati	Oxygen Radicals Mediate the Mutagenic Effects of UVA on Melanocytes
Dr. Aruna Basu	Metrohealth Medical Center	Functional Analysis of LKB1 Gene Linked to Peutz-Jeghers Syndrome
Dr. Han-Fei Ding	Medical College Of Ohio	Capase-8 and p53 in N-Myc-Induced Sensitization to Apoptosis
Dr. Zhongwu Guo	Case Western Reserve University	Glycoengineering Cancer Cells for Selective Immunotargeting of Cancer
Dr. Xinhua Lin	Children's Hospital Research Foundation	Role of Dally-like, a Drosophila Glypican in Cell-Cell Signaling
Dr. Andrew Lowy	University Of Cincinnati	Tcf/beta catenin transactivation in gastric cancer
Dr. Shiuh Wen Luoh	University Of Cincinnati	HER-2/NEU Amplification In Human Breast Cancer
Dr. Vladimir Popik	Bowling Green State University	Development of Two-Photon Photoactivatable Enediyne Antibiotics
Dr. Lakshmidevi Pulakat	Bowling Green State University	AT2-Mediated Regulation of the ErbB2/3 in Breast Cancer
Dr. Lirim Shemshidini	University Of Toledo	Isolation of Repressors of the Androgen Receptor
Dr. Cynthia Smas	Medical College Of Ohio	Function of the HLH Protein Id-1 in Prostate Cancer
Dr. Michael Vogelmbaum	The Cleveland Clinic Foundation	Regulation of Apoptosis in Glioma Primary Cell Cultures
Dr. Susan E. Waltz	Children's Hospital Research Foundation	Ron in Skin Cancer
Dr. Michael E. Weinstein	The Ohio State University	Functions of Smad2 in Mesodermal Differentiation and Tumor Progression

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